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Antibodies

Recombinant beta III Tubulin Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301935L-50UL
100 ul
£402.00
AN301935L-100UL
About this Product
SKU:
AN301935L
Additional Names:
FEOM;beta;CFEOM;CDCBM;CDCBM1;CFEOM3;CFEOM3A;FEOM3;TUBB4;beta-4;beta Tubulin III;TUBB3;beta 3 tubulin;M(beta)3;M(beta)6;MC1R;Neuron specific beta III Tubulin;Neuron-specific class III beta-tubulin;QccE-11995;QccE-15186;TBB3;Tubb 3;Tubulin beta 3;Tubulin beta 3 chain;Tubulin beta 4;Tubulin beta III;Tubulin beta-3 chain;Tubulin beta-4 chain;Tubulin beta-III
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A651
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Beta III Tubulin (TUBB3) is one of six B Beta-tubulin isoforms and is expressed highly during fetal and postnatal development (axon guidance and maturation). Its expression levels decrease in the adult central nervous system (CNS) but remain high in the peripheral nervous system (PNS). Microtubules enriched in B Beta3-tubulin are more dynamic than those composed of other B Beta-tubulin isoforms. Research studies have shown that mutations in the B Beta3-tubulin gene TUBB3 cause ocular motility defects and other nervous system disorders. Furthermore, B Beta3-tubulin is present in neoplastic but not in normal differentiated glial cells. Thus, B Beta3-tubulin is a great neuronal marker.
Host:
Rabbit
Immunogen:
Recombinant human beta III Tubulin fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies