Recombinant GLUT3+GLUT14 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301929L-50UL
100 ul
£402.00
AN301929L-100UL
About this Product
- SKU:
- AN301929L
- Additional Names:
- GTR;Solute carrier family;Glucose transporter type;facilitated glucose transporter member;Solute Carrier Family 2 (Facilitated Glucose Transporter) Member;SLC2A;SLC2A3;GLUT3;facilitated glucose transporter member 3;FLJ90380;Glucose transporter type 3;Glucose transporter type 3 brain;GLUT 3;GLUT-3;GTR3;Solute carrier family 2;Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3;brain
- Application:
- Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A645
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- A group of related glucose transporters (Glut1-5 and 7) mediate the facilitated diffusion of glucose in nonepithelial mammalian tissues. Glucose transporter 3 (Glut3), also known as SLC2A3, has a higher affinity for glucose than the ubiquitous glucose transporter Glut1. In the normal brain, Glut3 expression is limited to neurons, whereas Glut1 is expressed in both neurons and glia. Glioblastoma-derived brain tumor initiating cells (BTICs) express increased levels of Glut3, enabling their survival in the microenvironment deficient in glucose. In addition, Glut3 expression levels correlate with poor survival in brain tumors. Glucose transporter 4 (Glut4) is a 12-transmembrane domain protein that facilitates glucose transport in the direction of the glucose gradient. This transporter localizes to intracellular organelles (endosomes) in unstimulated cells and translocates to the cell surface following insulin stimulation. Translocation of Glut4 is dependent on Akt, which may act by phosphorylating AS160, a RabGAP protein involved in membrane trafficking.The antibody can detect both GLUT3 and GLUT4.
- Host:
- Rabbit
- Immunogen:
- Recombinant human GLUT3+GLUT14 fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_glut3+glut14_monoclonal_antibody-an301929l
