Recombinant Rab8A Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301923L-50UL
100 ul
£402.00
AN301923L-100UL
About this Product
- SKU:
- AN301923L
- Additional Names:
- RAB;RAB8A;MEL;RAB8;AA409338;Mel transforming oncogene;Mel transforming oncogene (derived from cell line NK14);Mel transforming oncogene (derived from cell line NK14) RAB8 homolog;Mel transforming oncogene (RAB8 homolog);MGC124948;Oncogene c mel;Oncogene c-mel;RAB8A member RAS oncogene family;Ras associated protein RAB8;Ras related protein Rab 8A;Ras-related protein Rab-8A
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A639
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The Rab8 GTPase is a member of the Ras superfamily that functions in protein transport and membrane restructuring. RAB8 has two isoforms, RAB8A and RAB8B, that share 40% amino acid identity in the C-terminal variable region. RAB8 activity is regulated by specific guanine nucleotide exchange factors (GEFs), that mediate GTP loading, and GTPase activating proteins (GAPs) that convert them into the inactive GDP-bound form. RAB8 participates in recycling of the A Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors to the dendritic spine surface as well as in the intracellular transport of the metabotropic glutamate receptor type 1 in neuronal cells. Rab8 is activated at the base of the cilium by its guanine nucleotide exchanger Rabin8.
- Host:
- Rabbit
- Immunogen:
- Recombinant human Rab8A fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_rab8a_monoclonal_antibody-an301923l
