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Antibodies

Recombinant Clusterin beta Chain Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301900L-50UL
100 ul
£402.00
AN301900L-100UL
About this Product
SKU:
AN301900L
Additional Names:
KUB;AAG;Ku70-binding protein;Sulfated glycoprotein;Complement-associated protein SP;Testosterone-repressed prostate message;NA1/NA;SGP;CLU;AAG4;APO-J;APOJ;CLI;CLU1;CLU2;KUB1;NA1/NA2;SGP-2;SGP2;SP-40;TRPM-2;TRPM2;clusterin;CLUS;Aging-associated gene 4 protein;Apolipoprotein J;Complement cytolysis inhibitor;Complement-associated protein SP-40;Ku70-binding protein 1;Sulfated glycoprotein2;Testosterone-repressed prostate message 2;Complement cytolysis inhibitor a chain;Clusterin alpha chain;Complement cytolysis inhibitor b chain;APOJ CLI;Sulfated glycoprotein 2
Application:
Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A616
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Clusterin (CLU) also named as apolipoprotein J, is a multifunctional glycoprotein that is expressed ubiquitously in most tissues. Clusterin functions as a secreted chaperone protein that interacts with and stabilizes stress-induced proteins to prevent their precipitation. Research studies show that clusterin plays a protective role in Alzheimer's disease by sequestering amyloid B Beta (1-40) peptides to form long-lived, stable complexes, which prevents amyloid fibril formation.In addition to the secreted protein, several intracellular isoforms are localized to the nucleus, mitochondria, cytoplasm and ER. The subcellular distribution of these multiple isoforms leads to the diversity of clusterin functions. Additional studies report that clusterin is involved in membrane recycling, cell adhesion, cell proliferation, apoptosis, and tumor survival.
Host:
Rabbit
Immunogen:
Recombinant human Clusterin beta Chain fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies