Recombinant TFF1/pS2 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301892L-50UL
100 ul
£402.00
AN301892L-100UL
About this Product
- SKU:
- AN301892L
- Additional Names:
- TFF,pNR,HPS,D21S,Protein Ps,Trefoil factor,TFF1,BCEI,D21S21,HP1.A,HPS2,pNR-2,pS2,Breast cancer estrogen-inducible protein,Polypeptide P1.A,Protein Ps2,Trefoil factor 1
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A608
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- TFF1/pS2 is a gastric peptide that is highly expressed by mucosal goblet cells of the stomach, where it is thought to play a role in maintaining the integrity of the epithelial layer of the mucosa through the regulation of cell-cell adhesion and cell migration. Research studies have shown that TFF1 functions as a tumor suppressor in the stomach as its expression is frequently lost in gastric carcinomas, largely due to promoter hypermethylation. Research studies have also demonstrated that TFF1 is a transcriptional target of estrogen receptor-A Alpha and that TFF1 expression in breast carcinoma may be used as a predictive biomarker for response to anti-estrogen therapy.
- Host:
- Rabbit
- Immunogen:
- Recombinant human TFF1/pS2 fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:ps2_monoclonal_antibody-an301892l
