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Antibodies

Recombinant KIF5B Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301889L-50UL
100 ul
£402.00
AN301889L-100UL
About this Product
SKU:
AN301889L
Additional Names:
HEL-S;KIF5B;HEL-S-61;KINH;KNS;KNS1;UKHC
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A605
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
KIF5B is a member of kinesin superfamily protein 5 (KIF5). KIF5 consists of three family members referred to as KIF5A, KIF5B, and KIF5C. KIF5A and KIF5C are specifically expressed in neurons whereas KIF5B is expressed ubiquitously. Targeted disruption of the kif5B gene resulted in embryonic lethality. These and other studies demonstrate that KIF5B plays an important role in the localization and distribution of major organelles, including the mitochondria and lysosome, and can contribute to autophagy. In addition, gene rearrangements involving KIF5B fusions to ALK and RET have been identified as drivers for lung cancer and other malignancies.
Host:
Rabbit
Immunogen:
Recombinant human KIF5B fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies