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Antibodies

Recombinant UQCRFS1/RISP Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301884L-50UL
100 ul
£402.00
AN301884L-100UL
About this Product
SKU:
AN301884L
Additional Names:
RIS;RIP;UQCR;UQCRFS;UQCRFS1;RIP1;RIS1;RISP;UQCR5
Application:
Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A596
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Ubiquinol-cytochrome c reductase iron-sulfur subunit (UQCRFS1), also known as Rieske iron-sulfur protein (RISP), is a component of Complex III in the mitochondrial electron transport chain. UQCRFS1/RISP and two other subunits, cytochrome b (MT-CYB) and cytochrome c1 (CYC1), are essential for the catalytic activity of Complex III. Studies show that UQCRFS1/RISP is required for fetal mouse hematopoietic stem cell differentiation and adult mouse hematopoietic stem cell quiescence. In addition, loss of UQCRFS1/RISP decreases the strength of T cell receptor (TCR) signaling, indicating that this protein is critical for optimal TCR signaling.
Host:
Rabbit
Immunogen:
Recombinant human UQCRFS1/RISP fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies