Recombinant Glypican-3 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301865L-50UL
100 ul
£402.00
AN301865L-100UL
About this Product
- SKU:
- AN301865L
- Additional Names:
- MXR;GPC;UNQ;PRO;CDw;ADAM;Protein FOAP;Secreted glypican;Glypican proteoglycan;Sialic acid-binding Ig-like lectin;C20orf;OCI;GPC3;DGSX;GTR2-2;MXR7;OCI-5;SDYS;SGB;SGBS;SGBS1;glypican-3;CDw329;Glypican 3;Glypican proteoglycan 3;Glypican-3 [Precursor];GTR2 2;Heparan sulphate proteoglycan;Intestinal protein OCI 5;Intestinal protein OCI-5;OCI 5;Protein FOAP-9;Secreted glypican-3;Sialic acid-binding Ig-like lectin 9;SIGLEC9;Siglec-9;ADAM33;C20orf153;UNQ873;PRO1891;OCI5
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A577
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Glypican 3 belongs to Glypicans (GPCs), a family of glycosylphosphatidylinositol (GPI)-anchored heparan sulphate proteoglycans (HSPGs) that may play a role in the control of cell division and growth regulation. In mammals, there are six GPCs (GPC1 to GPC6), all of which have a similar core-protein size of approx. 60 kDa and the clustering of glycosaminoglycan attachment site near the C-terminus. They are tethered to the cell surface by GPI linkages, which can be cleaved by endogenous phospholipases, thus releasing the protein. Glypican 3 (GPC3) is highly expressed in many tissues during development and plays an important role in the regulation of embryonic growth. Loss-of-function mutations of GPC3 result in the Simpson-Golabi-Behmel overgrowth syndrome (SGBS), and Gpc-3 null mice display developmental overgrowth. In hepatocellular carcinoma (HCC), the overexpression of glypican 3 has been demonstrated to be a reliable diagnostic indicator.
- Host:
- Rabbit
- Immunogen:
- Recombinant human Glypican-3 fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_glypican_3_monoclonal_antibody-an301865l
