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Antibodies

Recombinant CX3CR1 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301864L-50UL
100 ul
£402.00
AN301864L-100UL
About this Product
SKU:
AN301864L
Additional Names:
GPR,CCRL,GPRV,CX3CR,CMKDR,CMKBRL,CX3CR1,CCRL1,CMKBRL1,CMKDR1,GPR13,GPRV28,V28,Beta chemokine receptor-like 1,CMK-BRL1,CMK-BRL-1,CX3C chemokine receptor 1,C-X3-C CKR-1,C-X3-C motif chemokine receptor 1,fractalkine receptor,G-protein coupled receptor 13
Application:
Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A576
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also known as GPR13 or V28. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12).
Host:
Rabbit
Immunogen:
Recombinant human CX3CR1 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies