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Antibodies

Recombinant TAF1 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301862L-50UL
100 ul
£402.00
AN301862L-100UL
About this Product
SKU:
AN301862L
Additional Names:
TAF;CCG;KAT;DYT;MRXS;NSCL;N-TAF;TAF(II);DYT3/TAF;TAF1;BA2R;CCG1;CCGS;DYT3;DYT3/TAF1;KAT4;MRXS33;N-TAF1;NSCL2;OF;P250;TAF(II)250;TAF2A;TAFII-250;TAFII250;XDP;DYT3/KAT4;N-NSCL2;TATA-box binding protein associated factor 1
Application:
Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A574
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
TBP (TATA-binding protein) is a ubiquitously expressed nuclear protein that functions at the core of the general transcription factor protein complex TFIID. TFIID, which contains TBP and 13 TBP-associated factors (TAFs), contributes to the formation of the transcription pre-initiation complex, an assembly of multiple protein complexes (TFIIA, TFIIB, TFIIE, TFIIF, TFIIH, and RNA polymerase II) that bind to a gene promoter during the initiation of transcription. Once the pre-initiation complex is formed, RNA polymerase II becomes competent for elongation and transcribes the body of a gene. TBP functions in the recruitment of TFIID by binding to the TATA-box sequence found approximately 25 base pairs upstream of the transcription start site of many protein-coding genes. In addition, many transcriptional activator proteins interact with TBP and various TAF proteins to facilitate recruitment of TFIID and formation of the pre-initiation complex.
Host:
Rabbit
Immunogen:
Recombinant human TAF1 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies