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Antibodies

Recombinant CD70 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301838L-50UL
100 ul
£402.00
AN301838L-100UL
About this Product
SKU:
AN301838L
Additional Names:
Tumor necrosis factor ligand superfamily member;TNFSF;CD70;CD27-L;CD27L;CD27LG;TNFSF7;TNLG8A;CD27 ligand;CD70 antigen;Tumor necrosis factor ligand superfamily member 7;Ki-24;CD27L;TNFSF7;CD 27L;CD 70;CD27 L;CD27 LG;CD70 molecule;Ki 24 antigen;Ki24 antigen;member 7;sCD27 Ligand;soluble CD27 Ligand;Surface antigen CD70;TNFSF 7;Tumor necrosis factor (ligand) superfamily
Application:
Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A550
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
CD70 is a type II transmembrane glycoprotein and a member of the tumor necrosis factor ligand superfamily (TNFSF), also known as CD27L and TNFSF7. It is normally expressed on medullary thymic epithelial cells. Its expression is induced on activated lymphoid cells (B cells, T cells, and NK cells) and dendritic cells. CD70 is a ligand for CD27, a co-stimulatory receptor that plays an important role in T cell activation and proliferation. CD70 overexpression has been reported in various tumors such as renal cell carcinoma, glioblastoma, and non-small cell lung carcinoma and it's being actively pursued as a therapeutic target.
Host:
Rabbit
Immunogen:
Recombinant human CD70 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies