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Antibodies

Recombinant Claudin 18.2 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301831L-50UL
100 ul
£402.00
AN301831L-100UL
About this Product
SKU:
AN301831L
Additional Names:
UNQ;PRO;CLDN;SFTA;Claudin;Claudin-;CLDN18;SFTA5;SFTPJ;Claudin-18;Claudin-18.2;UNQ778;PRO1572;SPJ
Application:
Immunohistochemistry
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A543
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Claudin 18 (CLDN18) belongs to the large claudin family of proteins, which are tetraspan transmembrane proteins of tight junctions. Claudins exhibit specific patterns of expression in different tissues. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. Altered CLDN18 expression has been reported in various human malignancies, including gastric cancer, lung adenocarcinoma, and pancreatic neoplasm.
Host:
Rabbit
Immunogen:
Recombinant human Claudin 18.2 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies