Recombinant CBX4 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301815L-50UL
100 ul
£402.00
AN301815L-100UL
About this Product
- SKU:
- AN301815L
- Additional Names:
- Cbx;CBX4
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A527
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- CBX4 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. CBX4 itself is a SUMO E3 ligase, and its function influences EMT, DNA damage response, tumor angiogenesis, and self-renewal. E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. It is involved in the SUMOylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression.
- Host:
- Rabbit
- Immunogen:
- Recombinant human CBX4 fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_cbx4_monoclonal_antibody-an301815l
