Recombinant Thymidylate Synthase Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301812L-50UL
100 ul
£402.00
AN301812L-100UL
About this Product
- SKU:
- AN301812L
- Additional Names:
- HST;OK/SW-cl;TYMS;HST422;TMS;TS;thymidylate synthase;OK/SW-cl.29;HST422;thymidylate synthase;TMS;thymidylate synthetase
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A524
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Thymidylate synthase is a homodimer composed of two 30 kDa subunits, which catalyze the methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), an essential step in the formation of thymine nucleotides. Thymidylate synthase is an intracellular enzyme that provides the sole de novo source of thymidylate, making it a required enzyme in DNA biosynthesis with activity highest in proliferating cells. Being the exclusive source of dTMP, investigators have concluded that TS is also an important target for anticancer agents such as 5-fluorouracil (5-FU). 5-FU acts as a TS inhibitor and is active against solid tumors such as colon, breast, head, and neck.
- Host:
- Rabbit
- Immunogen:
- Recombinant human Thymidylate Synthase fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_thymidylate_synthase_monoclonal_antibody-an301812l
