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Antibodies

Recombinant MTAP Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301807L-50UL
100 ul
£402.00
AN301807L-100UL
About this Product
SKU:
AN301807L
Additional Names:
HEL;MTAP;BDMF;DMSFH;DMSMFH;HEL-249;LGMBF;MSAP;c86fus;5' methylthioadenosine phosphorylase;5''-methylthioadenosine phosphorylase;Epididymis luminal protein 249;HEL 249;MeSAdo phosphorylase;Methylthioadenosine phosphorylase;MTA phosphorylase;MTAPase;S methyl 5 thioadenosine phosphorylase;S methyl 5' thioadenosine phosphorylase;S-methyl-5''-thioadenosine phosphorylase
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A519
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
MTAP is an enzyme essential for the salvage pathway for both adenine and methionine synthesis. MTAP catalyzes the cleavage of 5'-methylthioadenosine into adenine and 5-methylthio-D-ribose-1-phosphate. Adenine is then used to generate AMP whereas 5-methylthio-D-ribose-1-phosphate is converted into methionine. MTAP is expressed in all normal cells and tissues, although frequently lost in different human tumors including pancreatic adenocarcinoma, neuroendocrine tumors, non-small cell lung carcinoma and breast carcinoma, thereby implicating its potential function as a tumor suppressor.
Host:
Rabbit
Immunogen:
Recombinant human MTAP fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies