Recombinant PTPN12 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301790L-50UL
100 ul
£402.00
AN301790L-100UL
About this Product
- SKU:
- AN301790L
- Additional Names:
- PTPG;PTPN;PTPG1;PTP-PEST;PTPN12;PTP-PEST;Protein tyrosine phosphatase G1;Protein tyrosine phosphatase non receptor type 12;Protein-tyrosine phosphatase G1;PTN12;PTP PEST;Tyrosine protein phosphatase non receptor type 12;Tyrosine-protein phosphatase non-receptor type 12
- Application:
- Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A502
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility.
- Host:
- Rabbit
- Immunogen:
- Recombinant human PTPN12 fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_ptpn12_monoclonal_antibody-an301790l
