Recombinant ILF3 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301758L-50UL
100 ul
£402.00
AN301758L-100UL
About this Product
- SKU:
- AN301758L
- Additional Names:
- ILF;MMP;Mpp;DRBP;NF-AT;MPHOSPH;TCP;ILF3;CBTF;DRBF;DRBP76;MMP4;MPHOSPH4;MPP4;NF-AT-90;NF110;NF110b;NF90;NF90a;NF90b;NFAR;NFAR-1;NFAR2;TCP110;TCP80;Double stranded RNA binding protein 76;Double-stranded RNA-binding protein 76;Interleukin enhancer binding factor 3;Interleukin enhancer-binding factor 3;M phase phosphoprotein 4;M-phase phosphoprotein 4;NF AT 90;Nuclear factor associated with dsRNA;Nuclear factor of activated T cells 90 kDa;Nuclear factor of activated T-cells 90 kDa;Translational control protein 80
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A466
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Interleukin enhancer-binding factor 3 (ILF3) is a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms. ILF3 exists main two isoforms NFAR-1 (90 kDa) and -2 (110 kDa). Upon viral infection, ILF3 accumulates in the cytoplasm and participates in the innate antiviral response.
- Host:
- Rabbit
- Immunogen:
- Recombinant human ILF3 fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_ilf3_monoclonal_antibody-an301758l
