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Antibodies

Recombinant LSD2/AOF1 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301732L-50UL
100 ul
£402.00
AN301732L-100UL
About this Product
SKU:
AN301732L
Additional Names:
AOF;LSD;C6orf;AOF1;C6orf193;LSD2;KDM1B
Application:
Flow Cytometry, Immunofluorescence, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A440
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
LSD2, also known as AOF1, is a Lysine (K)-specific demethylase that is encoded by the KDM1B gene in human. LSD2 demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD2 demethylates both mono- and Dimethylated 'Lys-4' of histone H3. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.
Host:
Rabbit
Immunogen:
Recombinant human LSD2/AOF1 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies
Western Blot with LSD2/AOF1 Monoclonal Antibody at dilution of 1:1000. Lane 1: SH-SY5Y
Western Blot with LSD2/AOF1 Monoclonal Antibody at dilution of 1:2000. Lane 1: K-562
Immunofluorescent analysis of (4% Paraformaldehyde) fixed HeLa cells using anti-LSD2/AOF1 Monoclonal Antibody at dilution of 1:50.
Flow cytometric analysis of human LSD2/AOF1 expression on HeLa cells. Cells were stained with purified anti-Human LSD2/AOF1, then a Alexa Fluor 488-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.