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Antibodies

Recombinant PDK2 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301725L-50UL
100 ul
£402.00
AN301725L-100UL
About this Product
SKU:
AN301725L
Additional Names:
PDK;PDHK;Pyruvate dehydrogenase kinase isoform;Pyruvate dehydrogenase lipoamide kinase isozyme;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme;isozyme;PDK2;PDHK2;PDKII;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2;isozyme 2;mitochondrial;Pyruvate dehydrogenase kinase;Pyruvate dehydrogenase kinase isoform 2;Pyruvate dehydrogenase lipoamide kinase isozyme 2
Application:
Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A433
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2 (PDK2) is a kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. PDK2 Mediates cellular responses to insulin and plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability.
Host:
Rabbit
Immunogen:
Recombinant human PDK2 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies