Recombinant ClC-2 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301722L-50UL
100 ul
£402.00
AN301722L-100UL
About this Product
- SKU:
- AN301722L
- Additional Names:
- CIC;CLCN;EJM;EGI;CLC;ECA;CLCN2;CIC-2;CLC2;ECA2;ECA3;EGI11;EGI3;EGMA;EJM6;EJM8;LKPAT;clC-2
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A430
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- ClC-2 (chloride channel protein 2) is a transmembrane protein and functions as a voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. ClC-2 is highly expressed in adrenal gland and involved in the regulation of aldosterone production. The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis. Defects in this gene may be a cause of certain epilepsies.
- Host:
- Rabbit
- Immunogen:
- Recombinant human ClC-2 fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_clc_2_monoclonal_antibody-an301722l
