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Antibodies

Recombinant Thyroglobulin Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301675L-50UL
100 ul
£402.00
AN301675L-100UL
About this Product
SKU:
AN301675L
Additional Names:
TDH;TG;AITD3;TGN;AITD 3;hTG;TDH3;THYG;Thyroglobulin;AITD 3;AITD3;hTG;TDH3;Tg;TGN;THYG;Thyroglobulin
Application:
Flow Cytometry, Immunohistochemistry
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A378
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules.
Host:
Rabbit
Immunogen:
Recombinant human Thyroglobulin fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies
Immunohistochemistry of paraffin-embedded Human thyroid cancer using Thyroglobulin Monoclonal Antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded Human thyroid using Thyroglobulin Monoclonal Antibody at dilution of 1:1000.
Flow cytometric analysis of human Thyroglobulin expression on TT cells. Cells were stained with purified anti-Human Thyroglobulin, then a Alexa Fluor 488-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.