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Antibodies

Recombinant Phospho-PTP1B (Ser386) Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301643L-50UL
100 ul
£402.00
AN301643L-100UL
About this Product
SKU:
AN301643L
Additional Names:
PTPN;PTPN1;PTP1B
Application:
Immunofluorescence, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A346
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Host:
Rabbit
Immunogen:
Recombinant human Phospho-PTP1B (Ser386) fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies
Western Blot with Phospho-PTP1B (Ser386) Monoclonal Antibody at dilution of 1:2000. (-): 293T, (2): 293T+ calyculin A (100nM, 60min)
Western Blot with Phospho-PTP1B (Ser386) Monoclonal Antibody at dilution of 1:2000. (-): Jurkat, (2): Jurkat + Okadaic A+ calyculin A (100nM, 30min)
Immunofluorescent analysis of (100% Ice-cold methanol) fixed HeLa cells using anti-Phospho-PTP1B (Ser386) Monoclonal Antibody at dilution of 1:50.
Immunofluorescent analysis of (100% Ice-cold methanol) fixed SW480 cells using anti-Phospho-PTP1B (Ser386) Monoclonal Antibody at dilution of 1:50.