Recombinant PRMT5 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301635L-50UL
100 ul
£402.00
AN301635L-100UL
About this Product
- SKU:
- AN301635L
- Additional Names:
- IBP;JBP;SKB;PRMT;HRMT1L;HRMT1L5;IBP72;JBP1;SKB1;SKB1Hs;PRMT5;72 kDa ICln binding protein;72 kDa ICln-binding protein;ANM5;Histone synthetic lethal 7;Histone-arginine N-methyltransferase PRMT5;HMT1 hnRNP methyltransferase like 5;homolog of;Jak-binding protein 1;JBP 1;PRMT 5;Protein arginine methyltransferase 5;Protein arginine N methyltransferase 5;Protein arginine N methyltransferase 5 N terminally processed;Protein arginine N-methyltransferase 5;S. cerevisiae;S. POMBE;S. POMBE HOMOLOG OF;SHK1 KINASE BINDING PROTEIN 1;Shk1 kinase binding protein 1 homolog;Shk1 kinase/binding protein 1;Shk1 kinase-binding protein 1 homolog;SKB 1;SKB1 homolog;SKB1: SKB1 homolog (S. pombe)
- Application:
- Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A338
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
- Host:
- Rabbit
- Immunogen:
- Recombinant human PRMT5 fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_prmt5_monoclonal_antibody-an301635l
