Recombinant PRMT5 Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301635L-50UL
100 ul
£402.00
AN301635L-100UL
About this Product
- SKU:
- AN301635L
- Additional Names:
- IBP,JBP,SKB,PRMT,HRMT1L,HRMT1L5,IBP72,JBP1,SKB1,SKB1Hs,PRMT5,72 kDa ICln binding protein,72 kDa ICln-binding protein,ANM5,Histone synthetic lethal 7,Histone-arginine N-methyltransferase PRMT5,HMT1 hnRNP methyltransferase like 5,homolog of,Jak-binding protein 1,JBP 1,PRMT 5,Protein arginine methyltransferase 5,Protein arginine N methyltransferase 5,Protein arginine N methyltransferase 5 N terminally processed,Protein arginine N-methyltransferase 5,S. cerevisiae,S. POMBE,S. POMBE HOMOLOG OF,SHK1 KINASE BINDING PROTEIN 1,Shk1 kinase binding protein 1 homolog,Shk1 kinase/binding protein 1,Shk1 kinase-binding protein 1 homolog,SKB 1,SKB1 homolog,SKB1: SKB1 homolog (S. pombe)
- Application:
- Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A338
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
- Host:
- Rabbit
- Immunogen:
- Recombinant human PRMT5 fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_prmt5_monoclonal_antibody-an301635l
