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Antibodies

Recombinant PPP1CB Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301634L-50UL
100 ul
£402.00
AN301634L-100UL
About this Product
SKU:
AN301634L
Additional Names:
NSLH;PPP1CB;HEL-S-80p;PP-1B;PP1B;PP1beta;PPP1CD;NSLH2;beta isozyme;catalytic subunit;delta isoform;MGC3672;PP 1B;Protein phosphatase 1;Protein phosphatase 1 beta;Protein phosphatase 1 catalytic subunit beta isoform;Protein phosphatase 1 delta;Serine threonine protein phosphatase PP1 beta catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A337
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective.
Host:
Rabbit
Immunogen:
Recombinant human PPP1CB fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies
Western Blot with PPP1CB Monoclonal Antibody at dilution of 1:1000. Lane 1: A431, Lane 2: Jurkat, Lane 3: NIH/3T3, Lane 4: PC-12, Lane 5: Mouse brain, Lane 6: Rat brain
Immunohistochemistry of paraffin-embedded Human cervical cancer using PPP1CB Monoclonal Antibody at dilution of 1:100.
Immunofluorescent analysis of (4% Paraformaldehyde) fixed HeLa cells using anti-PPP1CB Monoclonal Antibody at dilution of 1:500.
Immunofluorescent analysis of (4% Paraformaldehyde) fixed NIH/3T3 cells using anti-PPP1CB Monoclonal Antibody at dilution of 1:500.
Flow cytometric analysis of human PPP1CB expression on HeLa cells. Cells were stained with purified anti-Human PPP1CB, then a Alexa Fluor 488-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.