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Antibodies

Recombinant PAX8 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301620L-50UL
100 ul
£402.00
AN301620L-100UL
About this Product
SKU:
AN301620L
Additional Names:
Paired box;Paired box gene;Paired domain gene;paired box homeotic gene;PAX;PAX8;OTTHUMP00000158659;OTTHUMP00000158660;OTTHUMP00000203723;OTTHUMP00000203724;Paired box 8;Paired box gene 8;paired box homeotic gene 8;Paired box protein Pax 8;Paired box protein Pax-8;Paired domain gene 8;PAX 8
Application:
Immunofluorescence, Immunohistochemistry
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A323
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
PAX8 is one of nine transcription factors within the PAX gene family. It has been observed to be expressed during embryonic development however expression attenuates after development in all but a few tissues. Research has indicated that over-expression of PAX proteins in general are not an initiating event in tumorgenesis however they may facilitate malignant development. PAX8 is expressed in 80-96% of all High-grade serous carcinomas (HGSC) and is commonly used as a marker for the disease. In addition PAX8 has become a useful biomarker for differentiating between mullerian mucinous and non-mullerian tumors. PAX8 has also been associated with neoplasms in the kidney and thyroid.
Host:
Rabbit
Immunogen:
Recombinant human PAX8 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies