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Antibodies

Recombinant ARPC5/p16 ARC Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301616L-50UL
100 ul
£402.00
AN301616L-100UL
About this Product
SKU:
AN301616L
Additional Names:
ARC;ARPC;dJ127C;ARPC5;ARC16;dJ127C7.3;p16-Arc
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A319
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
Host:
Rabbit
Immunogen:
Recombinant human ARPC5/p16 ARC fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies
Western Blot with ARPC5/p16 ARC Monoclonal Antibody at dilution of 1:2000. Lane 1: HeLa, Lane 2: HCT-116, Lane 3: SW480, Lane 4: Rat brain, Lane 5: Mouse brain, Lane 6: Mouse ovary
Immunohistochemistry of paraffin-embedded Human spleen using ARPC5/p16 ARC Monoclonal Antibody at dilution of 1:100.
Immunohistochemistry of paraffin-embedded Human endometrial cancer using ARPC5/p16 ARC Monoclonal Antibody at dilution of 1:100.
Immunofluorescent analysis of (4% Paraformaldehyde) fixed Neuro-2a cells using anti-ARPC5/p16 ARC Monoclonal Antibody at dilution of 1:50.
Flow cytometric analysis of human ARPC5/p16 ARC expression on MCF-7 cells. Cells were stained with purified anti-Human ARPC5/p16 ARC, then a Alexa Fluor 488-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.