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Antibodies

Recombinant LysRS Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301592L-50UL
100 ul
£402.00
AN301592L-100UL
About this Product
SKU:
AN301592L
Additional Names:
DFNB;KIAA;KARS;CMTRIB;DFNB89;KARS1;KARS2;KRS;EC 6.1.1.6;KARS 1;KARS 2;Lysine tRNA ligase;Lysine--tRNA ligase;LysRS;Lysyl-tRNA synthetase;SYK;KIAA0070
Application:
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A291
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3(Lys), the primer for reverse transcription initiation.
Host:
Rabbit
Immunogen:
Recombinant human LysRS fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies