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Antibodies

Recombinant Ku80 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301584L-50UL
100 ul
£402.00
AN301584L-100UL
About this Product
SKU:
AN301584L
Additional Names:
KUB;XRCC;G22P;XRCC5;KARP-1;KARP1;KU80;KUB2;Ku86;NFIV;G22P2
Application:
Immunohistochemistry
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A283
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Host:
Rabbit
Immunogen:
Recombinant human Ku80 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies