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Antibodies

Recombinant SETD1A Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301557L-50UL
100 ul
£402.00
AN301557L-100UL
About this Product
SKU:
AN301557L
Additional Names:
Set;KIAA;Set1;KMT2F;Set1A;SETD1A;KIAA0339;Histone-lysine N-methyltransferase SETD1A;hSET1A;KMT2F;Lysine N methyltransferase 2F;Lysine N-methyltransferase 2F;SET domain containing 1A;SET domain containing protein 1A;SET domain-containing protein 1A;SET1;Set1 Ash2 histone methyltransferase complex subunit SET1;Set1/Ash2 histone methyltransferase complex subunit SET1;SET1A
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A256
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
hSET1 is a component of the histone methyltransferase (HMT) complex, which is a member of the COMPASS family, has H3K4 methyltransferase activity, and is closely related to development and tumors. hSET1 can produce mono-, di- and Trimethylation at lys4 (K4) on histone H3. This activity is blocked by the pre-methylation of the transcription repressor K9, indicating that the SET1/ASH2 complex can cause crosstalk between K9 methylation and K4 methylation. SET1 protein may play a role in synaptic function and neuron development. In addition, hSET1 protein can affect the proliferation and apoptosis of leukemia cells, and promote differentiation into neutrophils, providing new ideas for the treatment of leukemia and other cancers.
Host:
Rabbit
Immunogen:
Recombinant human SETD1A fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies