Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Recombinant Histone H3 (NT) Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301549L-50UL
100 ul
£402.00
AN301549L-100UL
About this Product
SKU:
AN301549L
Additional Names:
Histone H;H3C;H3/A;H3C2;H3C3;H3C4;H3C6;H3C7;H3C8;H3FA;H3C10;H3C11;H3C12;HIST1H3A;H3C1;Histone H3.1;Histone H3/a;Histone H3/b;H3FL;HIST1H3B;H3FC;HIST1H3C;H3FB;HIST1H3D;H3FD;HIST1H3E;H3FI;HIST1H3F;H3FH;HIST1H3G;H3FK;HIST1H3H;H3FF;HIST1H3I;H3FJ;HIST1H3J;H3/A;H3FA;H3FB;H3FC;H3FD;H3FF;H3FH;H3FI;H3FJ;H3FK;H3FL;Hist1h3a;HIST1H3B;HIST1H3C;HIST1H3D;HIST1H3E;HIST1H3F;HIST1H3G;HIST1H3H;HIST1H3I;HIST1H3J;Histone H3.1;Histone H3/a;Histone H3/b;H3 histone family;H31;H3a;histone 1;Histone cluster 1;Histone H3/c;Histone H3/d;Histone H3/f;Histone H3/h;Histone H3/i;Histone H3/j;Histone H3/k;Histone H3/l;member A
Application:
ChIP, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A248
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Histones are a family of basic proteins that form the core of the nucleosome - the fundamental structural unit of chromatin. In a single nucleosome, core histone proteins H2A, H2B, H3, and H4 form an octamer around which the DNA is tightly wrapped. Histone proteins not only serve to compact chromosomal DNA but also play vital roles in the dynamic and long-term regulation of genes by a wide variety of post-translational modifications (PTMs). These PTMs including acetylation, methylation, phosphorylation, and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability and gene transcription. Among the histone members, histone H3 is the most extensively modified and its amino-terminal tail structure has been shown to be especially critical for eukaryotic cells.
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to the N-terminus of human histone H3 protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies
Immunohistochemistry of paraffin-embedded Human prostate hyperplasia using Histone H3 Monoclonal Antibody at dilution of 1:500.
Immunohistochemistry of paraffin-embedded Mouse colon using Histone H3 Monoclonal Antibody at dilution of 1:500.
Immunohistochemistry of paraffin-embedded Rat colon using Histone H3 Monoclonal Antibody at dilution of 1:500.
Immunofluorescent analysis of (100% Ice-cold methanol) fixed HeLa cells using anti-Histone H3 Monoclonal Antibody at dilution of 1:200.
Chromatin immunoprecipitation analysis of HeLa immunoprecipitated DNA by real-time PCR using primers specific for the human GAPDH-CDS, RPL30, LDHA-promoter, LDHA, FOXO3a-promoter, FOXO3a-downstream, TUBBP10. The data are presented as enrichment of each sample relative to the total amount of input chromatin at each amplicon.