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Antibodies

Recombinant GPNMB Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301540L-50UL
100 ul
£402.00
AN301540L-100UL
About this Product
SKU:
AN301540L
Additional Names:
UNQ;PRO;GPNMB;HGFIN;NMB;Glycoprotein nmb;Glycoprotein nmb like protein;Osteoactivin;Transmembrane glycoprotein;Transmembrane glycoprotein HGFIN;Transmembrane glycoprotein NMB;UNQ1725;PRO9925;Glycoprotein nmb like protein;Gpnmb;HGFIN;NMB;Osteoactivin;Transmembrane glycoprotein;Transmembrane glycoprotein HGFIN;Transmembrane glycoprotein NMB
Application:
Flow Cytometry, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A239
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
The protein is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant human GPNMB fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies
Western Blot with GPNMB Monoclonal Antibody at dilution of 1:1000. Lane 1: A375, Lane 2: B16-F0, Lane 3: EL4.IL-2, Lane 4: HeLa
Immunohistochemistry of paraffin-embedded Human tonsil using GPNMB Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Mouse small intestine using GPNMB Monoclonal Antibody at dilution of 1:1000.
Flow cytometric analysis of human GPNMB expression on A375 cells. Cells were stained with purified anti-Human GPNMB, then a Alexa Fluor 488-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.
Flow cytometric analysis of human GPNMB expression on EL4 cells. Cells were stained with purified anti-Human GPNMB, then a Alexa Fluor 488-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.