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Antibodies

Recombinant FBXW7 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301521L-50UL
100 ul
£402.00
AN301521L-100UL
About this Product
SKU:
AN301521L
Additional Names:
FBX,CDC,FBXO,hCdc,FBW,SEL,FBXW7,AGO,CDC4,FBW6,FBW7,FBX30,FBXO30,FBXW6,SEL-10,SEL10,hAgo,hCdc4,Archipelago,Archipelago homolog,DKFZp686F23254,Drosophila,Drosophila),E3 ubiquitin protein ligase,F box and WD 40 domain protein 7,F box and WD 40 domain protein 7 (archipelago homolog,F box and WD repeat domain containing 7,F box protein FBW7,F box protein FBX30,F box protein SEL 10,F box protein SEL10,F-box and WD repeat domain containing 7,F-box and WD-40 domain-containing protein 7,F-box protein FBX30,F-box/WD repeat-containing protein 7,FLJ16457,homolog of,Homolog of C elegans sel 10,Homolog of C.elegans sel10,S.cerevisiae,SEL 10
Application:
Immunofluorescence, Immunohistochemistry
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A220
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination.
Host:
Rabbit
Immunogen:
Recombinant human FBXW7 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies