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Antibodies

Recombinant EphA2 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301514L-50UL
100 ul
£402.00
AN301514L-100UL
About this Product
SKU:
AN301514L
Additional Names:
ARCC;CTPP;EPHA;Ephrin type-A receptor;CTRCT;ARCC2;CTPA;CTPP1;CTRCT6;ECK;EPHA2;Ephrin type-A receptor 2;Epithelial cell kinase;Tyrosine-protein kinase receptor ECK;AW545284;EPH receptor A2;Myk2;Sek2;Sek-2
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A213
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway.
Host:
Rabbit
Immunogen:
Recombinant human EphA2 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies