Recombinant Phospho-Cyclin D1 (Thr286) Monoclonal Antibody
Product Sizes
50 ul
£281.00
AN301503L-50UL
100 ul
£402.00
AN301503L-100UL
About this Product
- SKU:
- AN301503L
- Additional Names:
- Cyl;PRAD;U21B;CCND;B cell leukemia;G1/S specific cyclin D;Cyclin D;BCL;BCL1;D11S287E;PRAD1;U21B31;CCND1;Cyclin D1;B cell leukemia 1;BCL 1;Cd1;Cyl 1;G1/S specific cyclin D1;BCL1;D11S287E;PRAD1;U21B31;CCND1;Cyclin D1;cyclin D1
- Application:
- Flow Cytometry, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- A202
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner.
- Host:
- Rabbit
- Immunogen:
- Recombinant human Phospho-Cyclin D1 (Thr286) fragment
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_phospho_cyclin_d1_(thr286)_monoclonal_antibody-an301503l
