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Antibodies

Recombinant CD79a Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301486L-50UL
100 ul
£402.00
AN301486L-100UL
About this Product
SKU:
AN301486L
Additional Names:
CD79A;IGA;MB-1;CD79a molecule;CD79A antigen;MB1;MB1;Ig&alpha
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A181
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Host:
Rabbit
Immunogen:
Recombinant human CD79a fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies