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Antibodies

Recombinant alpha Actinin 4 Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301433L-50UL
100 ul
£402.00
AN301433L-100UL
About this Product
SKU:
AN301433L
Additional Names:
ACTN;Non-muscle alpha-actinin;ACTININ;ACTN4;ACTININ-4;FSGS;FSGS1;Non-muscle alpha-actinin 4;actinin 4;Actinin alpha 4;actinin4;ACTN 4;Alpha-actinin-4;DKFZp686K23158;F actin cross linking protein;F-actin cross-linking protein;Focal segmental glomerulosclerosis 1;FSGS 1;Non muscle alpha actinin 4
Application:
Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A128
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA.
Host:
Rabbit
Immunogen:
Recombinant human Actinin 4 fragment
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies