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Antibodies

Recombinant Histone H2A (Acetyl Lys5) Monoclonal Antibody

Product Sizes
50 ul
£281.00
AN301414L-50UL
100 ul
£402.00
AN301414L-100UL
About this Product
SKU:
AN301414L
Additional Names:
H2AFM;HIST1H2AB;H2AFA;HIST1H2AE;H2AC4;H2AC8
Application:
ChIP, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
A109
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Histone post-translational modifications (PTMs), known as the "histone code", are key mechanisms of epigenetics that modulate chromatin structures. The PTMs on histone including acetylation, methylation, phosphorylation, and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability and gene transcription. Histone acetylation, tightly controlled by the opposing action of histone acetyltransferases (HATs) and histone deacetylases (HDACs), occurs primarily at lysine residues on the N-terminal tails of histones H2A (Lys5, 9, and 15), H2B (Lys5, 12, 15, 16, and 20), H3 (Lys4, 9, 14, 18, 23, 27, and 36), and H4 (Lys5, 8, 12, 16, and 20), and plays vital roles in the regulation of gene expression, DNA damage repair, chromatin dynamics, etc.
Host:
Rabbit
Immunogen:
Acetylated human histone H2A (Lys5) peptide
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies