Recombinant LDLR Monoclonal Antibody
Product Sizes
100 ul
£346.00
AN301402L-100UL
About this Product
- SKU:
- AN301402L
- Additional Names:
- LDLCQ;LDLR;FH;FHC;LDLCQ2;low-density lipoprotein receptor;Familial Hypercholesterolemia;LDL R;LDL receptor;FHC;LDLCQ2;low-density lipoprotein receptor
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B1169
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human LDLR protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_ldlr_monoclonal_antibody-an301402l
