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Antibodies

Recombinant SREBP-1 Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN301398L-100UL
About this Product
SKU:
AN301398L
Additional Names:
BHLHD;SREBP;SREBF;BHLHD1;SREBP1;SREBF1
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B1165
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
Host:
Rabbit
Immunogen:
Recombinant Human SREBP-1 protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies