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Antibodies

Recombinant Rb Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN301387L-100UL
About this Product
SKU:
AN301387L
Additional Names:
PPP1R;OSRC;PPP1R130;RB;p105-Rb;pRb;pp110;RB1;Exon 17 tumor GOS561 substitution mutation causes premature stop;GOS563 exon 17 substitution mutation causes premature stop;Osteosarcoma;P105RB;PP105;Prepro retinoblastoma associated protein;Protein phosphatase 1 regulatory subunit 130;RB transcriptional corepressor 1;RB1 gene;retinoblastoma 1;Retinoblastoma protein;Retinoblastoma suspectibility protein;Retinoblastoma-associated protein
Application:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B1154
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Host:
Rabbit
Immunogen:
Recombinant Human Rb protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies