Recombinant 53BP1 Monoclonal Antibody
Product Sizes
100 ul
£346.00
AN301369L-100UL
About this Product
- SKU:
- AN301369L
- Additional Names:
- 53BP;TDRD;tumor protein p53 binding protein;p53BP;TP53BP;TP53BP1;53BP1;TDRD30;TP53;p202;p53BP1;tumor protein p53 binding protein 1;53BP1;p202;p53BP1;TDRD30;TP53;tumor protein p53 binding protein 1
- Application:
- Cell-based/Functional Assay, ChIP, ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B1136
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human 53BP1 protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_53bp1_monoclonal_antibody-an301369l
