Recombinant ALK Monoclonal Antibody
Product Sizes
100 ul
£346.00
AN301358L-100UL
About this Product
- SKU:
- AN301358L
- Additional Names:
- NBLST;ALK;CD246;NBLST3;Ki-1;Anaplastic lymphoma kinase;ALK;CD246;NBLST3
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B1125
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human ALK protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_alk_monoclonal_antibody-an301358l
