Recombinant MYPT1 Monoclonal Antibody
Product Sizes
100 ul
£346.00
AN301350L-100UL
About this Product
- SKU:
- AN301350L
- Additional Names:
- MYPT;PPP1R12A;M130;MBS;MYPT1;Myosin binding subunit;Myosin phosphatase target subunit 1;Myosin phosphatase targeting subunit 1;Myosin phosphatase-targeting subunit 1;Protein phosphatase 1;Protein phosphatase 1 regulatory inhibitor subunit 12A;Protein phosphatase 1 regulatory subunit 12A;Protein phosphatase myosin binding subunit;Protein phosphatase myosin-binding subunit;regulatory (inhibitor) subunit 12A
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B1117
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human MYPT1 protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_mypt1_monoclonal_antibody-an301350l
