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Antibodies

Recombinant ASC Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN301342L-100UL
About this Product
SKU:
AN301342L
Additional Names:
TNS;TMS;CARD;A;Asc;TMS-;TNS1;masc;CARD5;TMS-1;9130417A21Rik;Pycard;9130417A21Rik;Asc;CARD5;masc;TMS-;TMS-1;TNS1
Application:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B1109
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant Mouse ASC protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies