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Antibodies

Recombinant Insulin Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN301325L-100UL
About this Product
SKU:
AN301325L
Additional Names:
MODY,IDDM,IDDM1,IDDM2,ILPR,IRDN,MODY10,INS,Insulin,Connecting Peptide,Insulin A chain,Insulin B chain,Preproinsulin,Proinsulin,Proinsulin precursor,IDDM,IDDM1,IDDM2,ILPR,ins,INS,Insulin A chain,Insulin B chain,IRDN,MODY10,Preproinsulin,Proinsulin,Proinsulin precursor,Pro-Insulin
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B1088
Clonality:
Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5&apos, region and with the IGF2 gene at the 3&apos, region. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant Human Insulin protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies