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Antibodies

Recombinant Phospho-4E-BP1 (Thr37/46)) Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN301307L-100UL
About this Product
SKU:
AN301307L
Additional Names:
4EBP;eIF4E binding protein;eukaryotic translation initiation factor 4E-binding protein;4E-BP;EIF4EBP;EIF4EBP1;4E-BP1;4EBP1;BP-1;PHAS-I;eukaryotic translation initiation factor 4E-binding protein 1;BP 1;eIF4E binding protein 1;eIF4E-binding protein 1;PHASI;Phosphorylated heat- and acid-stable protein regulated by insulin 1;4EBP1;4E-BP1;BP-1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;4E BP1
Application:
ELISA, Immunofluorescence, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B1070
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to residues around (Thr37/46) of Human Phospho-4E-BP1
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies