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Antibodies

Recombinant Phospho-IGF1R (Tyr1135/1136)/Phospho-Insulin Receptor B Beta (Tyr1150/1151) Monoclonal Antibody

Product Sizes
100 ul
£346.00
AN301299L-100UL
About this Product
SKU:
AN301299L
Additional Names:
HHF;CD220;HHF5;INSR;IR;Insulin R;INSR;IR;Insulin Receptor;IGF IR;Insulin Receptor B Beta
Application:
ELISA, Immunofluorescence, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B1062
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to residues around (Tyr1135/1136)/(Tyr1150/1151) of Human Phospho-IGF1R/Phospho-Insulin Receptor B Beta
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies