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Antibodies

Recombinant Actinin-A Alpha1 Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN301292L-50UL
100 ul
£346.00
AN301292L-100UL
About this Product
SKU:
AN301292L
Additional Names:
ACTN;Non-muscle alpha-actinin;BDPLT;ACTN1;BDPLT15;Alpha-actinin cytoskeletal isoform;F-actin cross-linking protein;Non-muscle alpha-actinin-1;actinin;actinin 1 smooth muscle;Actinin alpha 1;ACTN 1;alpha 1;Alpha Actinin 1;Alpha actinin cytoskeletal isoform;Alpha-actinin-1;F actin cross linking protein;FLJ40884;FLJ54432;Non muscle alpha actinin 1;Actinin-A Alpha1
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B1055
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant Human Actinin-A Alpha1 protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies