Recombinant GluR-2 Monoclonal Antibody
Product Sizes
50 ul
£246.00
AN301279L-50UL
100 ul
£346.00
AN301279L-100UL
About this Product
- SKU:
- AN301279L
- Additional Names:
- GRIA;GLUR;GluA;HBGR;GluR-K;GRIA2;GLUR2;GLURB;GluA2;GluR-K2;HBGR2;AMPA 2;AMPA selective glutamate receptor 2;AMPA2;AMPA-selective glutamate receptor 2;GLUR 2;GLUR B;GluR K2;GluR-2;GluR-B;Glutamate receptor 2;Glutamate receptor ionotropic;Glutamate receptor ionotropic AMPA 2;GluR-2
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- translate.label.attr.clone:
- B1042
- Clonality:
- Monoclonal, Recombinant Monoclonal
- Concentration:
- 0.2 mg/ml
- Extra Details:
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human GluR-2 protein
- Isotype:
- IgG, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:p-recombinant_glur_2_monoclonal_antibody-an301279l
