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Antibodies

Recombinant GPX1 Monoclonal Antibody

Product Sizes
50 ul
£246.00
AN301163L-50UL
100 ul
£346.00
AN301163L-100UL
About this Product
SKU:
AN301163L
Additional Names:
GPX;Gpx-;Glutathione peroxidase;GPXD;GSHPX1;GPX1;GPx-1;GSHPx-1;Glutathione peroxidase 1;Cellular glutathione peroxidase;GPX1
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
translate.label.attr.clone:
B922
Clonality:
Monoclonal, Recombinant Monoclonal
Concentration:
0.2 mg/ml
Extra Details:
The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site.
Host:
Rabbit
Immunogen:
Recombinant Human GPX1 protein
Isotype:
IgG, kappa
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Recombinant Antibodies